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A Comparative Effectiveness Study of PTSD Treatments Among Sexual and Gender Minority Populations

RecruitingNAAges 18 Years - anyAllStanford University
NCT06367764 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is see if Cognitive Processing Therapy and STAIR Narrative Therapy work to treat posttraumatic stress disorder (PTSD) among lesbian, gay, bisexual, transgender, queer/questioning, intersex, asexual/aromantic, and all other sexual or gender minority (LGBTQIA+) adults. The main questions it aims to answer are: * Do these treatments reduce PTSD symptoms in LGBTQIA+ patients? * Do these treatments help improve quality of life and reduce depression in LGBTQIA+ patients? * Do stress from stigma and discrimination and drug/alcohol use change the impact of the treatment on PTSD symptoms? * Are LGBTQIA+ patients satisfied with these treatments? Do these treatments work differently among different groups within the LGBTQIA+ community? * Do LGBTQIA+ patients complete these treatments? Study participants will receive one of these two PTSD treatments. Participants wi

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. 18 years of age or older 2. Currently live in California 3. Ability to understand study procedures and to comply with them for the entire length of the study 4. Ability to understand a written informed consent document and the willing to sign it 5. Ability to speak and read English or Spanish 6. Identify as a sexual and/or gender minority 7. Score 33 or higher on the PTSD Checklist-5 (PCL-5) 8. Interest in getting treatment for PTSD 9. Not be in another concurrent psychotherapy treatment (group or individual) for PTSD (psychotherapy treatment for non-PTSD conditions is allowed). 10. Able to attend treatment sessions in person in San Francisco or have access to a device that allows for treatment via videoconferencing. Exclusion Criteria: 1. Contraindication to any study-related procedure or assessment 2. Clinically significant impairment which interferes with ability to fully participate in the study (including symptoms of schizophrenia, schizoaffective disorder, bipolar disorder, or other disorders) 3. Active suicidal intent
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What it tests

  • Cognitive Processing Therapy
  • STAIR Narrative Therapy
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Where

2 sites
Stanford University
Palo Alto, United States
UCSF Alliance Health Project
San Francisco, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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