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Resistance Training and Corticospinal Excitability in Multiple Sclerosis

RecruitingNAAges 18 Years - anyAllUniversity of Aarhus
NCT06374108 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of the present study is to investigate effects of progressive resistance training on central nervous system functioning (corticospinal excitability (CSE)) and walking capacity in persons with multiple sclerosis (pwMS). A total of 54 pwMS will be enrolled and randomized into 1 of 3 groups: high dose resistant training (RT), low dose RT, and waitlist control.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years * MS diagnosis according to the McDonald diagnostic criteria * Shows impairments in walking capacity * Ability to self transport to test and exercise Exclusion Criteria: * Pregnancy * Neurological or other comorbidities that affects the nervous system * Relapse within the past 2 months * Pacemaker or metallic implants * Hypertension (medically unregulated) * Participation in structured RT over the past 3 months (≥ 2 sessions/week).
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What it tests

  • Progressive resistance training
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Where

2 sites
Department of Public Health
Aarhus, Denmark
Department of Nutrition, Exercise and Sports, University of Copenhagen
Copenhagen, Denmark
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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