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Investigating the Plasticity of Human Predictive Coding Through Neuromodulation

RecruitingNAAges 18 Years - 35 YearsAllUniversità Vita-Salute San Raffaele
NCT06374433 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The hypothesis of the study is to investigate how different trm (tES) methods (transcranial Alternating Current Stimulation, tACS, and transcranial Random Noise Stimulation, tRNS) applied at different stimulation frequencies and networks can modulate the predictive mechanisms in human perception and cognition. This is an interventional, monocentric, cross-sectional randomized, single-blinded study on healthy adult volunteers, recruited through online advertisements, flyers and oral transmission. Volunteers will be recruited from the general population of young adults.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Participant is willing and able to give informed consent for participation in the study. * Aged 18-35 years. * Normal or corrected to normal vision, as per anamnestic investigation. Exclusion Criteria: * Participants with a diagnosis of epilepsy (as per anamnestic investigation). * Participants with major neurological disorders (as per anamnestic investigation). * Participants that are currently under psychopharmacological treatment with tricyclic antidepressants (as per anamnestic investigation). * Participants with metal implants in the brain, pacemakers, brain stimulators, cochlear implants (as per anamnestic investigation).
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What it tests

  • Occipital tACS at IAF-2Hz
  • Occipital tACS at IAF+2Hz
  • Frontal tACS at 4-7 Hz
  • Occipital tRNS
  • Frontal tRNS
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Where

1 site
Università Vita-Salute San Raffaele
Milan, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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