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Investigating the Tolerability and Feasibility of tVNS Following aSAH

RecruitingNAAges 18 Years - anyAllSheffield Teaching Hospitals NHS Foundation Trust
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In plain words

What the trial is, and whether it could suit you

After a subarachnoid haemorrhage, complications are common and increase the overall rate of disability and death from the condition. Despite some advances in preventing, detecting and treating these complications, the rates of complications and associated risks remain high. Further research into ways to reduce complications of subarachnoid haemorrhage. Transcutaneous vagus nerve stimulation (tVNS) is a technique where a small handheld device is attached to an earpiece which stimulates the nerves to the ear. This is given for short periods and may help improve blood flow and reduce inflammation in the brain. The intervention has been safely used and licensed in seizures, headache and severe depression. This study will look to see if it is feasible and tolerable to have tVNS twice daily for 5 days after subarachnoid haemorrhage, and whether it can help reduce the risk of complications fr

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age \>18 * Admitted to STH (Sheffield Teaching Hospital) neurosurgery department * Confirmed aneurysmal SAH on vascular imaging * Within 5 days of 'Securing' aneurysm (i.e., successfully coiled or surgically following rupture) Exclusion Criteria: * Current or prior use of a vagus nerve stimulation * Symptomatic bradycardia or PPM insertion * Complete heart block * Implantation of any other electrical stimulator (e.g. DBS)
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What it tests

  • Transcutaneous Vagus Nerve Stimulation
  • Sham Transcutaneous Vagus Nerve Stimulation
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Where

1 site
University of Sheffield
Sheffield, United Kingdom
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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