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Italian iTTP Registry

Recruitingn/aAges 12 Years - 99 YearsAllFondazione Luigi Villa
NCT06376786 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

ItaliTTP is an observational, prospective, single-arm, national, multicenter, non-pharmacological cohort study aimed at better defining and understanding the natural history, disease severity, and clinical outcomes of patients with immune-mediated thrombotic thrombocytopenic purpura (iTTP) in Italy. A minimum of 132 consecutive patients with acute iTTP (first event or relapse) will be enrolled for 3 years, with the possibility of extension, with a follow-up period of 3 years.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with an acute iTTP episode (first event or relapse), defined by thrombocytopenia and microangiopathic hemolytic anemia, in the absence of alternative causes, and the presence of severe deficiency of ADAMTS13 activity (\< 10 IU/dL or \<10% of normal value) and anti-ADAMTS13 autoantibodies * Both male and female patients, aged 12 years or older * Patients who have signed the informed consent for the participation to the study Exclusion Criteria: * Patients who have not signed the informed consent for the participation to the study
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What it tests

  • Not listed
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Where

1 site
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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