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โ† Trials
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Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR

RecruitingPhase 3Ages 18 Years - anyAllWake Forest University Health Sciences
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In plain words

What the trial is, and whether it could suit you

The purpose of this prospective, randomized, double-blinded study is to further evaluate the safety and efficacy of varying doses of intravenous magnesium in the treatment of AFF RVR.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age \> 18 years or older * Able to provide informed consent * Primary diagnosis AFF RVR greater than or equal to 120 bpm * Diltiazem as rate control agent * English speaking Exclusion Criteria: * Hemodynamically unstable patients (SBP \<90, MAP \<65) * Impaired consciousness * End stage renal disease on hemodialysis or peritoneal dialysis * Acute heart failure exacerbation based on clinical diagnosis, physician exam, bedside echo, and/or additional imaging * Patient in AFF RVR that is highly suspected to be a compensatory mechanism for an alternative clinical diagnosis * Rhythms other than AF, such as sick sinus syndrome or wide-complex ventricular response * Acute myocardial infarction * Pregnancy defined as a positive urine HCG (human chorionic gonadotropin) * Contraindications to magnesium sulfate (including myasthenia gravis) * Allergy or sensitivity to any study drugs * Previously enrolled in this trial during a different patient encounter * Withdrew from study
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What it tests

  • Magnesium Sulfate 2 G
  • Magnesium Sulfate 4 G
  • Saline
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Where

1 site
Advocate Christ Medical Center Emergency Department (ACMC ED)
Oak Lawn, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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