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Investigating Micro-Manipulation Procedures for Assisted Hatching Timing

RecruitingNAAges 18 Years - 42 YearsFemaleReproductive Medicine Associates of New Jersey
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In plain words

What the trial is, and whether it could suit you

This study aims to assess the clinical significance of cleavage stage (Day 3) assisted hatching compared to assisted hatching at the blastocyst stage (Day 5,6,7) of embryo development at the time of trophectoderm (TE) biopsy for patients undergoing in vitro fertilization (IVF) and preimplantation genetic testing for aneuploidy (PGT-A) for treatment of their infertility.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria for participants: 1. Patients undergoing an IVF cycle with plan for subsequent FET of a single euploid embryo 2. \<4 2PNs prior to randomization 3. Female partners age \<42 years old at start of VOR cycle 4. Normal ovarian reserve: 1. AMH โ‰ฅ 1.2 ng/mL 2. AFC โ‰ฅ 8 3. FSH โ‰ค 12IU/L 5. BMI \<38 6. Patients who desire to transfer the best quality embryo for their embryo transfer. Exclusion Criteria for participants: 1. All patients who do not voluntarily give their written consent for participation 2. Patients with a prior failed IVF cycle - defined as no blastocysts 3. Patients with a history of more than one failed euploid embryo transfer 4. Donor oocyte cycles 5. Gestational Carriers 6. Male partner with \<100,000 total motile spermatozoa per ejaculate (donor sperm is acceptable) 7. Use of surgical procedures to obtain sperm 8. Communicating hydrosalpinges without a plan for surgical correct prior to frozen embryo transfer 9. Endometrial Insufficiency, as defined by a prior cycle with maximal endometrial thickness \<6mm,), or persistent endometrial fluid 10. Single gene disorders, chromosomal translocations, or any other disorders requiring a more detailed embryo genetic analysis than standard PGT-A
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What it tests

  • Laser Assisted Hatching
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Where

1 site
Reproductive Medicine Associates of New Jersey
Marlton, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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