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Advanced Surgical Simulation Processes in the Correction of Skeletal Defects and Deformities

RecruitingNAAges 2 Years - 40 YearsAllIstituto Ortopedico Rizzoli
NCT06380530 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Virtual Surgical Planning (VSP), Computer-Aided Surgical Simulation (CASS) for bone corrections, and the customization of implants and devices through 3D printing, known as Patient-Specific Instruments (PSI) and Graft-Specific Instruments (GSI), are assuming increasingly central roles in orthopedic clinical and surgical practice. One area witnessing notable advancement is the treatment of musculoskeletal disorders (MMS) in children, adolescents, and young adults. These disorders involve severe and rare abnormalities in skeletal formation and development across three-dimensional planes, often affecting multiple limbs. Managing such deformities is complex, challenging to standardize, and prone to unpredictable clinical, radiographic, and functional outcomes. The application of 3D modeling and printing technologies offers a deeper understanding of deformities and facilitates improved pred

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of musculoskeletal disease (MSD) of the limbs; * Need for mono- or polyaxial correction by one or more osteotomies; * Presence of specific consent to participate in the trial; Exclusion Criteria: * Patients who refuse to participate in the study * Patients who do not undergo radiological follow-up examinations for VSP or for whom the radiological record is insufficient to conduct VSP; * Patients who undergo different interventions for correction of MSD (growth modulation interventions by epiphysiodesis and hemiepiphysiodesis, progressive correction by external circular/hexapodal fixation); * Pregnant or lactating women
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What it tests

  • Deformity correction
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Where

7 sites
IRCCS Istituto Ortopedico Rizzoli
Bologna, Italy
Istituto Clinico Humanitas
Rozzano, Italy
Istituto Giannina Gaslini
Genova, Italy
Galeazzi Orthopedic Institute
Milan, Italy
Policlinico San Matteo
Pavia, Italy
Istituto Nazionale Tumori Regina Elena
Roma, Italy
Ospedale Pediatrico Bambino Gesù
Roma, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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