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โ† Trials
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VEin of MArshall Ethanolization Vs Extended Pulmonary Vein PULSEd Field Ablation After Failed PVI for Persistent AF

RecruitingNAAges 18 Years - anyAllSebastien Knecht
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to compare two ablation techniques to treat patients with persistent atrial fibrillation (irregular and often very rapid heart rhythm). An ablation is a procedure during which some scars are made on the inside of the heart to break up the electrical signals that cause the irregular heartbeat. In this trial researchers will compare a new technique, which uses tiny electric shocks to make the scars, to the standard technique, which uses heat. The main question the trial aims to answer is: โ€ข Does the new technique work as well as the standard technique to prevent the irregular heartbeat from returning within one year of the procedure? Participants will: * Undergo an ablation with either the new or the standard technique * Visit the hospital 1, 3, 6, 9 and 12 months after the procedure for a check-up * Wear a device to register their heart rhythm for 24

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Symptomatic persistent atrial fibrillation (AF) despite a first PVI. Persistent AF is defined as the presence of AF lasting โ‰ฅ7 days (i.e. in case of new onset AF one has to wait for 7 days) Exclusion Criteria: * Persistent AF lasting โ‰ฅ 12 months * Advanced valvular heart disease * Left atrial (LA) volume \>150mL * LA diameter (PS-LAX) \>60mm * Septal wall diameter \>15mm * Life expectancy \<1 year * Weight \>150 kg * Any contra indication to catheter ablation
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What it tests

  • Pulsed field ablation with posterior wall isolation
  • Radiofrequency ablation and vein of Marshall ethanolization
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Where

1 site
AZ Sint-Jan Brugge AV
Bruges, Belgium
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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