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Sand Play - the Effect of Biodiversity Exposure on Atopic Dermatitis

RecruitingNAAges 2 Years - 5 YearsAllNatural Resources Institute Finland
NCT06390696 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The prevalence of atopic dermatitis has increased along with urbanization and biodiversity loss. According to biodiversity hypothesis, the main reason is urban lifestyle and reduced contact to microbial diversity. Previous studies indicate association between atopic dermatitis and exposure to natural microbes in childhood. Sand Play - the Effect of Biodiversity Exposure on Atopic Dermatitis will investigate whether the exposure to microbial diversity in sandbox reduces the symptoms of atopic dermatitis, alters commensal microbiota and modifies immune regulation in children.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Eczema Area and Severity Index ≥ 2 Exclusion Criteria: * Eczema Area and Severity Index \< 2 * Immune deficiencies, i.e., antibody deficiency * Immunosuppressive systematic medications * A disease affecting immune response (e.g., colitis ulcerosa, rheumatoid arthritis, Crohn's disease, diabetes) * Cancer diagnosis * Topical medication for the treatment of atopic dermatitis during the trial * Disability affecting the immune response (e.g. Down's syndrome) * Non-participation in the national vaccine program * Participation in another intervention or follow-up study
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What it tests

  • Microbial intervention
  • Placebo
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Where

2 sites
Natural Resources Institute Finland
Helsinki, Finland
Tampere University
Tampere, Finland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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