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Obesity Management for Kidney TRANSPLANTation: OK-TRANSPLANT 2

RecruitingPhase 4Ages 18 Years - anyAllWestern University, Canada
NCT06396416 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

OK-TRANSPLANT 2 is a vanguard study for a large randomized, pragmatic, open-label trial. We will randomize participants with obesity, high-risk CKD/dialysis who are hoping for lose weight for the purpose of kidney transplant. Subjects will either be enrolled on a virtual weight management program or continue their usual care.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged 18 years or older * BMI; 35 kg/m\^2 * 10% risk of ESKD requiring renal replacement therapy over 2 years or receiving dialysis Exclusion Criteria: * Known contraindication to a GLP-1RA (pancreatitis, personal or family history of medullary thyroid cancer, hypersensitivity) * Type 1 diabetes * No access to semaglutide via drug coverage * Pregnant, breastfeeding or planning to become pregnant * Currently in a GLP-1RA or GLP-1RA/GIP study or planning to be in one
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What it tests

  • Semaglutide
  • Virtual Weight Management Coaching
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Where

1 site
London Health Sciences Centre
London, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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