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Transcutaneous Vagus Nerve Stimulation in Aphasia After Stroke

RecruitingNAAges 18 Years - anyAllSheffield Teaching Hospitals NHS Foundation Trust
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In plain words

What the trial is, and whether it could suit you

Aphasia is an acquired language disorder. Stroke is the most common cause of aphasia, which affects 30% of stroke survivors. Speech and Language Therapy (SLT) can help people with aphasia but it may not be provided at the required intensity. Access to therapy is often limited after the first few months following stroke. People with aphasia can improve with therapy many years after stroke but these benefits have not been found to translate to day to day conversation. Transcutaneous Vagus Nerve Stimulation (tVNS) is a non-invasive technique which involves stimulating a branch of the vagus nerve through the skin of the ear, using a small earpiece. This technique is safe and has been approved for use in headache. There is promising evidence that tVNS can improve motor rehabilitation in chronic stroke. This technique may be helpful in aiding language recovery in individuals with chronic apha

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Supratentorial stroke at least 6 months prior to recruitment * Aphasia (with word finding difficulties) * Ability to engage in the programme (support can be provided for cognitive or receptive difficulties) * Sufficient vision to engage in the computer-based SLT programme Exclusion Criteria: * Implanted devices (e.g. pacemaker) or implanted stimulation devices * Currently receiving a programme of Speech and Language Therapy (SLT) * Damage to the vagus nerve * Symptomatic bradycardia/ 2nd or 3rd heart block * Pregnancy * Unable to speak English * Severe deafness (despite using hear aids)
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What it tests

  • Transcutaneous Vagus Nerve Stimulation
  • Sham Transcutaneous Vagus Nerve Stimulation
  • Computer Based Speech and Language Therapy (Step by Step)
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Where

1 site
Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield, United Kingdom
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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