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Effect of Lidocaine on Postoperative Pain and Long-term Survival in Elderly Patients Undergoing Colorectal Surgery

RecruitingNAAges 60 Years - anyAllWest China Hospital
NCT06405776 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is a further observation and follow-up of the patients enrolled in the registration number NCT05920980 to further evaluate the effect of long-term infusion of lidocaine on postoperative chronic pain, long-term quality of life and survival rate in patients undergoing colorectal cancer surgery.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Participants were at least 60 years old; 2. American Society of Anesthesiologists (ASA) physical status I to III; 3. Body-mass index of 18-30 kg/m2; 4. Scheduled for elective colorectal surgery. Exclusion Criteria: 1. Metastases occurring in other distant organs; 2. Severe hepatic insufficiency (aspartate aminotransferase or alaninetransaminase or bilirubin \>2.5 times the upper limit of normal); 3. Renal impairment (creatinine clearance \<60 mL/min); 4. Cardiac rhythm disorders or systolic heart failure (second-and thirddegree heart block, ejection fraction \<50%); 5. Allergies to any of the trial drugs; chronic opioid use; 6. Inability to comprehend numeric rating scale.
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What it tests

  • lidocaine
  • Placebo
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Where

1 site
China
Sichuan, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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