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Collection of Primary Human

RecruitingNAAges 18 Years - 90 YearsAllUniversity Hospital, Tours
NCT06407102 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Treatment and prevention of respiratory infections are of great interest in many medical areas. Create a physical device covered by primary human nasal cells could be very usefull in order to analyse delivery and efficiency of drugs. In this context the aim of this project is to create a collection of primary cells from the human nasal epithelium. This collection will be realised during programmed surgery, thanks to a specific device dedicated to collect nasal cells. Then the cells will be sent to the lab in order to grow at the air-liquid interface, which is an excellent 'ex vivo' model for their study.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult patients (age \> 18 years) whose native language is French, or who understands French. * Affiliation with a French social security system (CMU accepted). * Informed consent, written and signed by the participant. * Planned rhinological surgery (meatotomy, septoplasty or turbinoplasty for example, but other surgeries as well) Exclusion Criteria: * Patients under court protection, guardianship or curatorship. * Pregnant or breast-feeding women (positive pregnancy test for women of childbearing age). * Patients presenting a major alteration of the mucosa or a malignant rhinosinus pathology.
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What it tests

  • Collection of nasal cells during programme surgery
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Where

1 site
AUSSEDAT
Tours, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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