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Ischaemic Lesions in Acute Intracerebral Haemorrhage

Recruitingn/aAges 18 Years - 120 YearsAllUniversity of Leicester
NCT06410274 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of this observational study is to determine how and why inadequate brain blood flow occurs after bleeding in patients with intracerebral haemorrhage (ICH). Treatment for strokes caused by burst blood vessels involves reducing blood pressure (BP) to stop the bleeding. However, this reduction in BP may affect blood flow, causing blockages in blood vessels within the brain. Fast breathing also affects brain blood flow. Therefore, participants will be asked to undergo a simple brain blood flow assessment using transcranial Doppler (TCD) within 48 hours upon admission to hospital. Patients will then have a follow-up TCD assessment at 4-7 days post-ICH onset, in addition to an MRI scan at \>7 days. This research will help to confirm if blockages after bleeding are caused by reduced blood flow within the brain.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Clinical diagnosis of a haemorrhagic stroke on CT imaging within 48 hours of onset (for patients waking with a stroke, time of onset will be taken to be the time when the patient was last asymptomatic). * Male or female, aged 18 years or above. Exclusion Criteria: * MRI imaging is contraindicated or unlikely to tolerate scanning process due to clinical instability (GCS \<8, unable to lie supine). * Patients requiring anaesthesia. * Male or Female, aged under 18 years. * Clinical diagnosis of stroke greater than 48 hours from onset
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What it tests

  • Transcranial Doppler ultrasonography (TCD)
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Where

1 site
University Hospitals of Leicester NHS Trust
Leicester, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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