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Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia

RecruitingEARLY Phase 1Ages 18 Years - 70 YearsFemaleUniversity of Missouri-Columbia
NCT06417177 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to examine hypoxic vasodilation and the role of beta-adrenergic receptors in younger premenopausal, perimenopausal, and older postmenopausal women.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Female assigned at birth * Pre, peri- or post-menopausal * Healthy weight (BMI ≥18 and ≤30 kg/m2) Exclusion Criteria: * Male (assigned at birth) * Pregnancy, breastfeeding * Use of hormone replacement therapies * Hysterectomy * Body mass index \>30 kg/m2 * Diagnosed sleep apnea * Current smoking/Nicotine/Drug use * Nerve/neurologic disease * Cardiovascular, hepatic, renal, respiratory disease * Blood pressure ≥140/90 mmHg * Diabetes, Polycystic ovarian syndrome * Communication barriers * Prescription medications * Malignant cancer
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What it tests

  • Placebo
  • Propranolol
  • Gemtesa
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Where

1 site
University of Missouri-Columbia
Columbia, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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