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Milk And Growth In Children (MAGIC) Born Very Preterm: A Randomized Trial

RecruitingNAAges 6 Hours - 4 DaysAllUniversity of Alabama at Birmingham
NCT06420531 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this multi-center randomized, parallel group trial is to determine the effect of human milk diets ranging between 180 and 200 mL/kg/day on the body composition outcomes of moderately preterm infants born between 27 and 31 weeks of gestation.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Gestational age between 27 0/7 and 31 6/7 weeks * Birthweight of 1500 grams or less * Human milk feeding during the first 14 days after birth * Full enteral feeding (120mL/kg/day or more) within the first 14 days after birth Exclusion Criteria: * Necrotizing enterocolitis stage 2 or greater * Spontaneous intestinal perforation * Major congenital/chromosomal anomalies * Terminal illness requiring limited or withheld support * Intention to restrict fluid intake after the first 14 postnatal days due to the presence of a symptomatic patent ductus arteriosus (PDA) * Any formula feeding within the first 14 days after birth
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What it tests

  • Human milk
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Where

4 sites
University of Alabama at Birmingham
Birmingham, United States
University of Mississippi Medical Center
Jackson, United States
University of Texas Southwestern Medical Center at Dallas
Dallas, United States
University of Texas Health Science Center at Houston
Houston, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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