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Ampicillin and Ceftriaxone for the Treatment of Enterococcus Faecalis Infective Endocarditis.

RecruitingPhase 4Ages 18 Years - anyAllFundación Pública Andaluza para la gestión de la …
NCT06423898 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Phase IV, open-label, randomized and multicenter clinical trial to prove that patients with Enterococcus faecalis infective endocarditis treated with an antibiotic treatment as a continuous infusion is non-inferior to the standard treatment, usually administered in hospitalized patients.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult patients * Possible or definitive diagnosis of infective endocarditis due to Enterococcus faecalis * Signed informed consent of patients Exclusion Criteria: * Allergy to penicillins or cephalosporins * Pregnancy and lactation * Polymicrobial infection including microorganisms different to E. faecalis
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What it tests

  • Ampicillin plus ceftriaxone in continuous infusion
  • Ampicillin plus ceftriaxone in intermittent infusion of 14 days, after which the treatment may be changed
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Where

18 sites
Hospital Universitario de Álava
Alava, Spain
Hospital Universitario de Cruces
Barakaldo, Spain
Hospital Universitario Vall d'Hebron
Barcelona, Spain
Hospital Clínico de Barcelona
Barcelona, Spain
Hospital Universitario de Donostia
Donostia / San Sebastian, Spain
Hospital Universitario Virgen de las Nieves
Granada, Spain
Hospital San Pedro
Logroño, Spain
Hospital Universitario Gregorio Marañón
Madrid, Spain

…and 10 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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