Microbiome Molecular Charaterisation

Inclusion Criteria: 1. Male \>=18 years. 2. Eastern Cooperative Oncology Group (ECOG) performance status (PS) 0 - 2. 3. Undergoing investigation for diagnosis, or with a proven diagnosis of prostate cancer and undergoing further investigation or clinical trial participation. 4. Patients with tumour deemed by the designated investigator as safely suitable for fresh biopsy AND who are medically fit (according to local practice) to undergo a biopsy or surgical procedure to acquire tumour tissue. 5. Willing and able to comply with the requirements of the sample collection including fresh tumour biopsy. 6. The subject is capable of understanding and complying with the protocol requirements and has given written informed consent. 7. A record of PSA levels within last 3 months. Exclusion Criteria: 1. The presence of any haematological disorders, including coagulation disorders, which would be a contraindication if patient were to undergo a biopsy. 2. Any psychiatric illness/social situations that would limit compliance with study requirements. 3. Presence of any concurrent condition or situation, which, in the investigator's opinion, may put the patient at significant risk, may confound the study results, or may interfere significantly with the patient's participation in the study.