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Application of HFNC for the Prevention of Hypoxemia During Perioperative Anesthetic-induced Intubation in Children: A Randomized Controlled Clinical Trial

RecruitingNAAges 2 Years - 10 YearsAllHenan Provincial People's Hospital
NCT06425406 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Compared with adults, children have higher metabolic needs, and the airway is more likely to collapse. Before tracheal intubation after anesthesia induction, the patient 's spontaneous breathing completely disappears. At this critical stage, the residual oxygen of the lung is consumed, resulting in hypoxemia and atelectasis. Therefore, it is necessary to explore the best oxygenation strategy during intubation. In addition, ultrasound has become a common equipment in the operating room. It has the advantages of portability, repeatability, and no radiation, and can provide strong support for the diagnosis of gastric distension.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 2-10 years old; * American Society of Anesthesiologists (ASA) Level I or II; * Children with healthy lungs and hearts; * Clear headed and able to cooperate with anesthesiologists for treatment. Exclusion Criteria: * Contraindications for HFNC: (1) Complete obstruction of the upper respiratory tract; (2) Skull base fracture or nasal bone fracture; (3) Patients who refuse to use HFNC; * The American Society of Anesthesiologists (ASA) rating is greater than Level II; * Children with upper respiratory tract infections within 2 weeks; * Pulmonary dysfunction, congenital heart disease in children;
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What it tests

  • high-flow nasal cannula
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Where

1 site
Department of Anaesthesiology and Perioperative Medicine, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital
Zhengzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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