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Effect of Resistance Training in Patients on the Waiting List for Heart Transplant

RecruitingNAAges 18 Years - 70 YearsAllUniversity of Sao Paulo General Hospital
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In plain words

What the trial is, and whether it could suit you

The present longitudinal, randomized, and blinded clinical trial aims to: * Evaluate the effects of resistance training on the functional capacity, quality of life, and cardiac biomarkers of hospitalized patients with heart failure (HF) on the waiting list for heart transplantation (HTx). * Evaluate the associations between Fried's frailty classification and functional capacity responses to resistance training. The protocol will have a total duration of 12 weeks.

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📋 Eligibility rules (as published)
Inclusion Criteria: * patients included in heart transplant list ≤1 month * hemodynamically stable in the last 48 hours defined as mean arterial pressure (MAP) ≥ 60 mmHg and ≤ 120 mmHg and - Heart rate (HR) ≥ 60 bpm and ≤ 120 mmHg. * dobutamine dose ≤ 10 mcg/kg/min Exclusion Criteria: * heart failure of arrhythmogenic and/or restrictive etiology * presence of uncontrolled acute arrhythmias * cognitive, orthopedic, or neuromotor changes that prevent functional tests from being carried out
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What it tests

  • Resistance Training Program
  • Standard Treatment Group
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Where

1 site
Instituto do Coração - Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
São Paulo, Brazil
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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