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โ† Trials
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International Care Bundle Evaluation in Cerebral Hemorrhage Research

RecruitingPhase 4Ages 18 Years - anyAllRegion Skane
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In plain words

What the trial is, and whether it could suit you

Spontaneous intracerebral haemorrhage (ICH) accounts for approximately 10-15% of all strokes but stands for 50% of stroke-related morbidity and mortality. Approximately half of all patients with ICH have a decreased level of consciousness at hospital admission. Despite this, intensive care and neurosurgical interventions are uncommon. A study conducted in low- and middle-income countries has demonstrated a beneficial effect of a treatment package consisting of early intensive blood pressure lowering, as well as the treatment of pyrexia and elevated blood glucose levels. The I-CATCHER team is now planning to conduct a similar study in Sweden and Australia, as well as in other high-income countries. The study has a clear focus on implementation, aiming to improve treatment and prognosis for patients with ICH within a few years. The purpose of I-CATCHER is to investigate whether a structure

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Adults (age โ‰ฅ18 years) * Non-contrast computerized tomography (NCCT) imaging-verified diagnosis of spontaneous intracerebral haemorrhage * โ‰ค24 hours from symptom onset or presumed symptom onset (last seen well) Exclusion Criteria: * Previous care limitation * End-stage comorbidity with short life-expectancy (\<6 m; e.g. terminal cancer) * ICH caused by brain tumor or cerebral venous thrombosis * Clinical signs of brain herniation at first presentation (unresponsive patient with bilaterally fixed, maximally dilated pupils) * Pregnant women beyond 22 weeks gestation may only be included after thorough discussion with an obstetrician to determine risks vs benefit.
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What it tests

  • Reversal of Oral anticoagulation within 30 minutes
  • Early intensive blood pressure lowering
  • Treatment of pyrexia
  • Hyperglycemia treatment
  • Do-not-resuscitate (DNR) or withdrawal of care
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Where

54 sites
The University of Oklahoma Health
Oklahoma City, United States
Royal Adelaide Hospital
Adelaide, Australia
Monash Medical Centre
Clayton, Australia
The George Institute for Global Health
Sydney, Australia
Health Sciences North/Health Sciences North Research Institute
Greater Sudbury, Canada
Hamilton General Hospital
Hamilton, Canada
Ottawa Hospital Research Institute
Ottawa, Canada
Hong Kong University Hospital
Hong Kong, Hong Kong

โ€ฆand 46 more on ClinicalTrials.gov.

๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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