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Kidney Stone Inflammation

Recruitingn/aAges 18 Years - 70 YearsAllUniversity of Chicago
NCT06436235 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This observational study aims to look at the connections between kidney stones, insulin resistance, and inflammation. The researchers hypothesize that people who form calcium kidney stones and have insulin resistance may have higher levels of inflammation because they have more visceral fat (fat around the abdominal organs). The study will recruit 20 people who have had calcium kidney stones but don't have diabetes, and 20 healthy people who haven't had kidney stones. All the participants will come to the research center at the University of Chicago Medicine. Participants will have a dual-energy X-ray absorptiometry (DEXA) scan to measure their visceral fat, and give blood and urine samples. The blood will be tested for insulin resistance, inflammatory markers, and other metabolic factors. The urine will be analyzed for substances that increase kidney stone risk. The main goal is to se

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📋 Eligibility rules (as published)
Inclusion Criteria: * Stone formers: * Age 18-70 * History of at least one calcium-based kidney stone * Healthy Controls: * Age 18-70 * No history of kidney stone or family history of kidney stones Exclusion Criteria (for both groups): * History of primarily uric acid * Cysteine, or struvite stones * History of diabetes or impaired glucose tolerance * Previous thiazide use * Anyone on a medication that cannot be stopped that may affect urine composition * Previous bariatric surgery or ileostomy * Primary hyperparathyroidism and elevated serum calcium.
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What it tests

  • Not listed
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Where

1 site
University of Chicago Medical Center
Chicago, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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