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Understanding the Variation of Modern Endoscopic Ultrasound Use in Patients With Oesophageal Cancer (VALUE)

Recruitingn/aAges 16 Years - anyAllUniversity Hospital Southampton NHS Foundation Tr…
NCT06440174 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is an observational trial that will look at patients undergoing endoscopic ultrasound (EUS) in patients with oesophageal cancer and to determine the proportion of cases in which EUS changes disease management in these patients.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Patients aged 16 or above with first diagnosis of biopsy-confirmed oesophageal cancer. 2. Referred for EUS examination as part of standard of care investigations. 3. Tumour location in the oesophagus, or gastro-oesophageal junction (Siewert types I-III) 4. MDT decision that patient is potentially curable with radical treatment (e.g., endoscopic treatment, surgery +/- neoadjuvant therapy, or definitive chemoradiotherapy) 5. Prior staging with CT and PET-CT 6. Eastern Cooperative Oncology Group (ECOG) performance status 0-2 7. Clinical staging of T1-T4, N0-N3, M0 disease 8. Adenocarcinoma or squamous cell carcinoma (SCC) histopathological cell type Exclusion Criteria: 9. Recurrent or residual disease 10. Distant metastatic disease detected before EUS. 11. Previous oesophagectomy or oesophageal radiotherapy 12. Unable to undergo EUS examination. 13. Concurrent malignancy e.g., second primary tumour 14. Other histopathological cell type
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What it tests

  • endoscopic ultrasound
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Where

14 sites
Cwm Taf UHB
Abercynon, United Kingdom
Royal Bournemouth Hospital
Bournemouth, United Kingdom
Cambridge University NHS Foundation Trust
Cambridge, United Kingdom
Cardiff and Vale UHB
Cardiff, United Kingdom
Velindre University NHS Trust
Cardiff, United Kingdom
Glasgow Royal Infirmary
Glasgow, United Kingdom
Castle Hill Hospital
Hull, United Kingdom
Guy's and St Thomas' NHS Foundation Trust
London, United Kingdom

…and 6 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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