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To Compare the Efficacy and Safety of Using oXiris and M100 During CRRT

RecruitingNAAges 18 Years - anyAllMohd Zulfakar Mazlan, MBBS
NCT06440759 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study aimed to compare the efficacy of Oxiris (Baxter) and M100 filters on IL-6 as primary outcomes and other blood cell counts, blood biochemistry (serum urea, creatinine, potassium, sodium), inflammation indicators (CRP, PCT), as secondary outcomes and safety (28 days mortality as a primary outcome and coagulopathy, lifespan of filter, usage of vasopressor, clinical conditions (ventilator-free days, ICU and hospital- length of stay) as a secondary outcome), clinical conditions (ventilator-free days, ICU and hospital- length of stay), and mortality of patients with pneumonia-related AKI.

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📋 Eligibility rules (as published)
Inclusion Criteria: * All adult patients aged\>18 years old * Diagnosis of septic shock * Diagnosis of KDIGO stage 3 acute renal failure Exclusion Criteria: * Moribund patient or patient that is expected to die within 72 hours * Pregnancy * patient with a bleeding tendency or known allergy to heparin
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What it tests

  • oXiris filter
  • M100 filter
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Where

1 site
Hospital Universiti Sains Malaysia (HUSM)
Kubang Kerian, Malaysia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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