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โ† Trials
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Senescent Endometrial Cells in Patients with Thin Endometrial Lining

Recruitingn/aAges 18 Years - 39 YearsFemaleTrio Fertility
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to determine if thin endometrial lining that is unresponsive to estrogen might be associated with the presence of senescent cells in patients following long-term use of oral contraceptives. The main question it aims to answer is: Are there any senescent cells present in thin endometrial lining? During the luteal phase of the cycle, participants will will undergo: * Gynecologic US to measure the endometrial lining thickness and pattern. * Endometrial biopsy with Pipelle catheter

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age 18-39 * BMI - up to 35 * Thin endometrium after OCP use * Asherman's syndrome * Women already undergoing endometrial biopsy for infertility testing (eg. EMMA testing) * Women with archived endometrial biopsy samples Exclusion Criteria: * Women with systemic disease (Rheumatic disease, DM) * Women with coagulopathies * Women with active pelvic inflammatory process * Uterine anomalies * Pregnant women * Any hormonal contraception use or IUD
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What it tests

  • Endometrial Biopsy
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Where

1 site
Trio Fertility
Toronto, Canada
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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