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Effect of Regional Anesthesia or Intravenous Infusion of Lidocaine on Morphine Use After Scoliosis Repair Surgery

RecruitingNAAges 12 Years - 25 YearsAllAssaf-Harofeh Medical Center
NCT06451562 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of the surgical correction of scoliosis is to prevent progression of the curve or progression of restrictive lung disease. After scoliosis surgery, patients experience severe pain. The standard treatment for pain relief after scoliosis surgery is the administration of opiates. However, treatment with these substances involves side effects such as respiratory depression, nausea and vomiting, inhibition of bowel activity and itching. To lower the dose of opiates, different types of painkillers and other techniques can be added. The purpose of the study is to compare the effect of instillation of lidocaine (which is an analgesic and anti-inflammatory) or regional anesthesia using Erector spinae plane on the dose of morphine consumption, the intensity of pain, the side effects and the quality of recovery during the first 48 hours after surgery to repair scoliosis.

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📋 Eligibility rules (as published)
Inclusion Criteria: Patients over the age of 12 with normal cognition, who are scheduled to undergo surgery to correct scoliosis and treatment with IV PCA independently for pain relief after surgery; The patients' parents/guardian (in the case of a minor) or the patient himself (in the case of an adult) signed an informed consent form for participation in the study; Patients should be able to operate the PCA device independently Exclusion Criteria: Patients who do not agree to participate in the study even if their parents signed an informed consent Patients who are unable to operate the PCA device independently Patients under treatment with opioids or cannabis for chronic pain for more than a month; Drug use of any kind; Alcoholism; Patients with depression, anxiety or post-trauma; Moderate-severe insufficiency of one of the systems - respiratory/cardiac/hepatic/renal; Sensitivity to one of the drugs in the research protocol.
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What it tests

  • Lidocaine
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Where

1 site
Shamir (Asaf Harofe) Medical Center
Be’er Ya‘aqov, Israel
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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