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Rapid MRI for Assessing Functional Abilities and Predicting TBI Outcomes

Recruitingn/aAges 18 Years - anyAllD.J Cook
NCT06454591 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Our project aims to develop a rapidly acquired and communicated MRI assessment and report that incorporates functional and structural imaging to convey information about functional neurological insults following traumatic brain injury (TBI) that are not typically visible on clinical imaging. Within this framework, there are two sub-studies. The first is a prospective study of patients with TBI who will have an MRI in the sub-acute period after their injury, followed by clinical assessments up to 90 days post-injury. A model will be developed to link MRI biomarkers to persistent symptoms of TBI. The second sub-study will use a focus group methodology to develop the report content and format with input from several groups of stakeholders.

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📋 Eligibility rules (as published)
Sub-acute MRI study Inclusion Criteria: \- Diagnosis of TBI Exclusion Criteria: * Self-reported history of brain surgery * Self-reported history of major neurologic, psychiatric or substance use disorder * Contraindications to MRI * Inability to follow-up at 30 and 90 days Focus group study Individuals with chronic TBI Inclusion Criteria: \- Diagnosis of TBI greater than one year prior Exclusion Criteria: \- Major neurologic, psychiatric or substance use disorder Caregivers of individuals with chronic TBI Inclusion Criteria: \- Relation who was diagnosed with TBI greater than one year prior that individual was the primary caregiver for Exclusion Criteria: \- Major neurologic, psychiatric or substance use disorder Clinicians who treat TBI Inclusion Criteria: \- Employment as a physician or allied health professional who has spent greater than 50% of their time treating TBI patients for at least two years of their career Exclusion Criteria: -N/A Inclusion Criteria: \- Employment as a personal injury lawyer or insurance adjuster who has spent greater than 50% of their time on TBI cases for at least two years of their career Exclusion Criteria: -N/A
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What it tests

  • Not listed
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Where

2 sites
University of Calgary
Calgary, Canada
Queen's University
Kingston, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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