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Clinical and Radiological Results of Long Term Tibial and Femoral Osteotomy in Knee Ostheoarthritis With Concomitant Lower Limb Malalignement

Recruitingn/aAges 18 Years - 70 YearsAllIstituto Ortopedico Rizzoli
NCT06462625 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The present study aims to evaluate the long-term and medium-term outcomes of different knee osteotomy techniques in the treatment of knee osteoarthritis in patients with lower limb malalignment. This evaluation is necessary in the current context of research on the treatment and prevention of knee osteoarthritis through treatments that do not involve or allow for the postponement of prosthetic replacement. Among the biological treatments performed in orthopedic clinical practice, osteotomy is one of the most promising. However, further long-term evaluations are needed to more clearly determine the indications and potential of this type of intervention, considering the various surgical procedures described for performing it.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Patients undergoing corrective knee osteotomy and any associated procedures such as meniscal repair/resection/replacement, ligament reconstruction, chondral treatment, or regenerative infiltrative treatment; 2. Patients aged between 18 and 70 years at the time of surgical intervention; 3. Patients with isolated compartmental osteoarthritis; 4. Patients with a varus or valgus knee alignment defect of at least 3° compared to mechanical neutrality. Exclusion Criteria: 1. Patients with advanced multicompartimental osteoarthritis; 2. Patients who are no longer reachable; 3. Women of childbearing age who cannot exclude pregnancy; 4. Patients unable to give informed consent or patients unwilling to sign the informed consent form.
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What it tests

  • High tibial osteotomy
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Where

1 site
IRCCS Istituto Ortopedico Rizzoli
Bologna, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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