Efficacy of Microparticle Geniculate Artery Embolization in Total Knee Prosthesis Patients With Pain Resistant to Medical Treatment. A Prospective Randomized Controlled Trial

Inclusion Criteria: * Man or woman aged between 40 and 80 years with a TKR for more than one year. * TKR pain with a VAS ≥ 40 mm having progressed for at least 3 months despite the initiation of a well-conducted medical treatment including stage I and II analgesics and NSAIDs in the absence of contraindication. * Investigations within 6 months to rule out malposition, loosening and sepsis (conventional X-rays, bone scan, knee CT scan and biological work-up for inflammatory syndrome). * No revision surgery envisaged. * Echodoppler hyperemia over the painful area of the knee. * Subjects affiliated to social security. * Signed consent to the study. Exclusion Criteria: * Local infection of the TKR or systemic infection. * Algoneurodystrophy. * Prosthesis loosening. * Neuropathic pain. * Allergy to contrast media. * Fibromyalgia. * Chronic or acute renal failure (clearance \< 30 ml/mn). * Hemostasis disorders (platelet count \< 50,000/mm3 or patient activated partial thromboplastin time (aPTT)/control aPTT\>1.2 or prothrombin ratio \< 50%). * Operative indication for removal of the prosthesis retained * Patient with severe obliterative arteriopathy of the lower limbs (Leriche et Fontaine stage 3). * Lidocaine contraindication: known hypersensitivity to lidocaine hydrochloride, amide-bonded local anesthetics or any of the excipients; patients with recurrent porphyria. * Vulnerable persons (minors, patients under guardianship or curatorship, deprived of liberty, under court protection, etc.). * Pregnant patients: for patients of childbearing age, a pregnancy test will be performed during the screening visit.