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OV Precision: Study Examining the Benefit of a Tumor- and Patient-specific Cancer Therapy

RecruitingNAAges 18 Years - anyFemaleSwiss GO Trial Group
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In plain words

What the trial is, and whether it could suit you

The long-term goal of this research project is to demonstrate whether HRD negative (HPDneg) patients benefit when additional multi-modal biological tumor information is incorporated into the molecular tumor board (mTB) treatment recommendation process.

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥ 18 years * Newly diagnosed EOC (adenocarcinoma of the ovary, peritoneum, and fallopian tube) and carcinosarcoma patients with a suspected FIGO Stage III and IV * No immediate need of systemic or surgical treatment at time of and until 2 weeks after diagnosis * Envisaged surgical candidate for interval debulking after 2 cycles of treatment * Patients have adequate hematology, liver and kidney functions * Willing and able to attend the visits, to understand the purpose of the trial and all trial-related procedures * ECOG 0-2 * Written informed consent according to national legal and regulatory requirements prior to any project specific procedures Exclusion Criteria: * ECOG ≥3 * Pregnant or lactating women * Any other malignancy within the last 5 years which has an impact on the prognosis of the patient * Concurrent participation in another clinical trial on the same indication * Any other serious underlying medical, psychiatric, psychological, familial, or geographical condition, which in the judgment of the sponsor-project leader may interfere with the project or affect patient compliance
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What it tests

  • Treatment recommendation by molecular tumorboard (mTB) based on tumor profiling
  • Carboplatin / Paclitaxel Chemotherapy
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Where

10 sites
Kantonsspital Baden AG
Baden, Switzerland
Universitätsspital Basel
Basel, Switzerland
HOCH Health Ostschweiz Kantonsspital St.Gallen
Sankt Gallen, Switzerland
Thurgau AG Frauenfeld / Münsterlingen
Frauenfeld, Switzerland
Kantonsspital Aarau AG
Aarau, Switzerland
Inselspital Bern (University Hospital for Medical Oncology)
Bern, Switzerland
HFR-Fribourg- Hopital Cantonal
Fribourg, Switzerland
Hirslanden Klinik St. Anna
Lucerne, Switzerland

…and 2 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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