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Changes in Attentional Control After a Focal Seizure.

Recruitingn/aAges 18 Years - 80 YearsAllUniversity Hospital, Lille
NCT06466681 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Epilepsy is frequently associated with cognitive and attentional disorders. Several studies have pointed out that there are modifications of brain activity in resting state during peri-ictal period in EEG and functional MRI. However, to date, no study has assessed the changes in attentional control after a seizure. The investigators hypothesize that a localized discharge is associated with a disorganization of the networks engaged in attentional control. In this regard, the investigators propose a prospective longitudinal study assessing the changes in attentional control after a focal seizure.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age superior to 18 and under 80 * Focal epilepsy with indication to pre-surgery work-up and 5 days programmed hospitalization dedicated to this work-up * Normal global cognitive performance (standard progressive Raven matrices score \> 5th percentile) * Be affiliated to the social security system * Have signed an informed consent Exclusion Criteria: * Pregnancy or breastfeeding * Not able to give consent (Article 1121-8 of the CSP) * Vulnerable person * Being deprived of liberty by judicial or administrative decision (Article L 1121-6 of the CSP) * Guardianship * Have a high probability of not respecting the protocol or of abandoning the study * Absence of any epileptic seizure recorded during the hospitalization * Recurrent seizures preventing the recording of at least 24 hours without any seizure following a seizure.
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What it tests

  • All included subjects
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Where

1 site
University Hospital,
Lille, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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