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Effects of Nutritional Support on Postoperative Delirium

RecruitingNAAges 65 Years - anyAllYonsei University
NCT06467552 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is a prospective, single-center, randomized controlled trial to compare whether applying nutritional supplementation therapy before and after surgery in elderly patients aged 65 years or older undergoing non-cardiac surgery can reduce the incidence of postoperative delirium.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Elderly patients aged 65 and above. * Patients undergoing non-cardiac major surgery in thoracic surgery, lung cancer surgery, multi-level spinal surgery in neurosurgery and orthopedics, or liver cancer surgery in hepatobiliary and pancreatic surgery, under general anesthesia with an expected surgery duration of 2 hours or more. * Patients scheduled for arterial catheterization. * Patients who are able to take oral intake from postoperative day #1. Exclusion Criteria: * Patients with uncontrolled systemic conditions such as diabetes, hypertension, renal disease, liver disease, and other systemic illnesses. * Those with visual impairment. * Patients with cognitive impairment based on the Mini-Mental State Examination for Dementia Screening criteria. * Individuals experiencing difficulty in communication. * Those diagnosed with neurological disorders (such as brain hemorrhage, stroke, brain tumor, dementia, Parkinson's disease, cognitive impairment, depression, etc.). * Patients diagnosed with alcohol or substance addiction. * Patients with cancelled scheduled surgeries. * Patients undergoing minor surgeries with expected anesthesia durations of less than 2 hours.
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What it tests

  • control group
  • Nucare Curact group
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Where

1 site
Yonsei University Health system, Severance Hospital
Seoul, South Korea
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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