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ADDICTOlogical Intervention in LIVEr Transplantation Recipients

RecruitingNAAges 18 Years - anyAllUniversity Hospital, Montpellier
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In plain words

What the trial is, and whether it could suit you

Transplantation for end-stage-liver disease (ESLD) in the context of Alcohol-Associated Liver Disease (AALD) has been increasing and represents the main indication for Liver Transplantation (LT) in the world. Alcohol Use Disorder (AUD) is considered a brain chronic disease and requires a transdisciplinary approach that includes medical treatment and behavioral interventions. In the context of LT, alcohol relapse occurs in 26 % up to 50% of LT recipients. Among Liver transplant recipients for AALD, severe alcoholic relapse (defined as more than 3 alcoholic drinks per day for women and 4/day for men) after LT leads to impaired longterm survival due to recurrent alcoholic cirrhosis (RAC), cardiovascular events and de novo cancer. Several strategies have been developed to prevent alcohol relapse. After LT, integrating an addiction team into the LT program has been advocated by the latest g

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Aged 18 years or above * Hospitalized for LT for AALD as primary, secondary or tertiary indication * Discharged from intensive care unit to hepatology or surgery wards Exclusion Criteria: * Severe alcohol-associated hepatitis as primary indication for liver transplantation * Impossibility of patient follow up over the next 2 years * General criteria: * Refusal or absence of informed consent, * Non-affiliation to the French national health insurance, * Persons placed under legal protection, guardianship or curatorship
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What it tests

  • Post-transplant addiction intervention
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Where

16 sites
Besançon University Hospital
Besançon, France
Bordeaux University Hospital
Bordeaux, France
Clermont Ferrand University Hospital
Clermont-Ferrand, France
Dijon University Hospital
Dijon, France
Lille University Hospital
Lille, France
Lyon University Hospital
Lyon, France
Marseille University Hospital
Marseille, France
Montpellier University Hospital
Montpellier, France

…and 8 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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