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Assessment of T-cell Response and In-vitro Proof-of-concept of T-cell Engineering in Chronic ESKD Patients.

Recruitingn/aAges 18 Years - anyAllCentre Hospitalier Régional d'Orléans
NCT06474169 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a comparative, prospective, non-interventional study to evaluate immune response in patients with chronic kidney disease. The primary objective is to define immunodeficiency (phenotype and function of T cells) in patients with end-stage kidney disease. The second objective is to provide an in-vitro proof-of-concept of T-cell engineering in the context of end-stage kidney disease. The study population was patients with chronic kidney disease.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Male or female ≥ 18 years 2. Informed participants who did not object to participating in the study Exclusion Criteria: 1. Chronic progressive infections 2. Prior organ transplantation (including bone marrow transplantation) 3. Previous treatment with immunosuppressive agents (such as Rituximab, Eculizumab, Tacrolimus or Ciclosporin, Cellcept or Imurel) within 2 years prior to inclusion 4. Participant under guardianship, curatorship or deprived of liberty 5. Pregnant or breastfeeding women
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What it tests

  • 1 blood sample for each participant
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Where

1 site
Center Hospitalier Universitaire d'Orléans
Orléans, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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