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Efficacy of Acetaminophen Alone Versus Combination of Acetaminophen/Ibuprofen After Cesarean Section

RecruitingPhase 4Ages 19 Years - anyFemaleSeoul National University Hospital
NCT06479122 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The investigators aim to compare the analgesic efficacy of intravenous acetaminophen alone versus combination of acetaminophen/ibuprofen (Maxigesic®IV) in multimodal analgesia after cesarean section.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients scheduled for elective cesarean section * Gestational age \> 37+0 weeks Exclusion Criteria: * Emergency cesarean section * Multiple pregnancy (e.g. twins, triplets) * Body weight \< 50 kg * Preeclampsia * History of hypersensitivity to acetaminophen or ibuprofen * History of upper gastrointestinal tract bleeding or gastric ulcer * Underlying liver disease * Underlying kidney disease or GFR \< 90 mL/min/1.73m2 * Heart failure or severe hypertension * History of asthma * Chronic use of barbital or tricyclic antidepressants
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What it tests

  • Acetaminophen
  • Acetaminophen/Ibuprofen
  • Acetaminophen
  • Acetaminophen/Ibuprofen
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Where

1 site
Seoul National University Hospital
Seoul, South Korea
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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