🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Compare the Efficacy and Outcome Between Fentanyl and Morphine as Analgo-sedation in Mechanically Ventilated Patients

RecruitingPhase 4Ages 18 Years - anyAllUniversiti Sains Malaysia
NCT06479655 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The primary aim of this clinical trial is to compare the effectiveness of fentanyl vs morphine as analgosedation in mechanically ventilated adult patients in the ICU. This study also aims to compare the outcomes of patients between the two groups. The main questions it aims to answer are : 1. Does propofol and fentanyl infusion as analgo-sedation achieve targeted sedation score at 12 and 24 hours compared to propofol and morphine infusion in mechanically ventilated adult patients in the intensive care unit (ICU)? 2. Is there a difference between the proportion of patients requiring rescue sedation dose between the fentanyl and morphine groups?

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Age \>18 years old * Patients who are expected by the ICU team to require invasive mechanical ventilation in ICU for at least more than 24 hours and for whom the ICU team decides to initiate continuous infusion of sedation * A patient who was ventilated and sedated not more than 12 hours before ICU admission. Exclusion Criteria: * Patients with chronic use of narcotics * Patients with chronic liver failure or end-stage renal failure * Patients with severe chronic neurocognitive dysfunction * Patients with drug overdose * Patients with a known allergy to either morphine or fentanyl * Patients who are receiving neuromuscular blockers * Patients who are pregnant * Patients who are diagnosed to have severe traumatic brain in
💊

What it tests

  • Fentanyl
  • Morphine
📍

Where

1 site
Hospital Universiti Sains Malaysia
Kota Bharu, Malaysia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy