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Pericardiotomy in Cardiac Surgery

RecruitingNAAges 18 Years - anyAllPopulation Health Research Institute
NCT06486636 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

PRINCE is an international, multicentre, randomized controlled trial of posterior pericardiotomy in patients without a history of atrial fibrillation (AF) or flutter undergoing cardiac surgery.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients greater than or equal to 18 years of age * Requiring surgical intervention on the proximal aorta, cardiac valves, and/or coronary arteries * Able to provide informed consent Exclusion Criteria: * History of atrial fibrillation or flutter * Cardiac surgery procedures not included in the inclusion criteria (planned ventricular assistance device, planned aortic arch, transplantation surgery) * Prior cardiac surgery requiring opening of the pericardium * Previous surgical instrumentation of the left pleural cavity * Patient undergoing minimally invasive cardiac surgery
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What it tests

  • Left Posterior Pericardiotomy
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Where

19 sites
University of Louisville
Louisville, United States
Weill Cornell Medicine
New York, United States
Baylor College of Medicine
Houston, United States
Medical University Vienna
Vienna, Austria
Medical University of Innsbruck
Innsbruck, Austria
Nova Scotia Health Authority - Halifax Infirmary
Halifax, Canada
Hamilton Health Sciences
Hamilton, Canada
St. Michael's Hospital
Toronto, Canada

…and 11 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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