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Shunt-dependency After aSAH - Role of Early Hyperglycaemia in CSF and Blood

Recruitingn/aAges 18 Years - anyAllIsabel Hostettler
NCT06486909 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this study is to confirm the association of early increased glucose levels in cerebro-spinal fluid (CSF) and ventriculo-peritoneal-shunt (VPS)-dependency also evaluating the influence of blood glucose on VPS dependency in patients suffering from an aneurysmal subarachnoid haemorrhage (aSAH). The main questions we aim to answer are: * Is there an association of glucose levels on VPS dependency in patients requiring extra-ventricular-drain (EVD) placement for aSAH? * In addition, if there is, what is the influence the course of glucose levels has on VPS dependency? Glucose levels in CSF and serum will be measured on admission, or in case of CSF, upon EVD placement. Glucose in CSF will then be measured every day until EVD removal together with serum glucose. Follow-up will be conducted in person after 3 and 6 months.

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📋 Eligibility rules (as published)
Inclusion Criteria: * 18 years old and older * Hospital admission due to an aneurysmal subarachnoid haemorrhage (radiological confirmation needed) Exclusion Criteria: * Younger than 18 years old * Non-aneurysmal subarachnoid haemorrhage (eg. trauma, perimesencephalic subarachnoid haemorrhage, mycotic or flow-associated aneurysms) * Previous enrolment into the current study
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What it tests

  • Cerebrospinal Fluid (CSF) Sample
  • Blood Serum Sample
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Where

3 sites
Cantonal Hospital Aarau
Aarau, Switzerland
University Hospital Basel
Basel, Switzerland
Cantonal Hospital St Gallen
Sankt Gallen, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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