🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Endoscopic Third Ventriculostomy vs. Ventriculoperitoneal Shunt in Idiopathic Normal Pressure Hydrocephalus (ENDOVEST)

RecruitingNAAges 40 Years - anyAllUniversity Hospital, Basel, Switzerland
NCT06488248 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The aim of this single-center, two-arm, open-labeled, randomized controlled clinical study is to compare two surgical interventions, endoscopic third ventriculostomy and ventriculoperitoneal shunt, in treating idiopathic normal pressure hydrocephalus in terms of clinical improvement.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * \>40 years of age * Symptom duration ≥3 months, \<24 months * No antecedent head trauma, ICH, meningitis, or other cause of secondary hydrocephalus * MUST show gait/balance disturbance, PLUS cognition impairment AND/OR urinary dysfunction. * Ventricular enlargement (Evans Index \> 0.3) not attributable to cerebral atrophy or congenital enlargement * No macroscopic obstruction to cerebrospinal fluid (CSF) flow Spinal Tap-Test * Opening pressure (on lateral decubitus): \<24cmH2O * Clinical improvement in at least one of the main symptoms after 40-50ml withdrawal of CSF Exclusion Criteria: * ≤40 years of age * No informed consent * Other neurologic, psychiatric or general medical condition which is sufficient to explain the presenting symptoms. * Previous cranial neurosurgical interventions * Other associated dementia syndromes * Incapacity to walk * Pregnancy and breastfeeding women
💊

What it tests

  • Endoscopic third ventriculostomy (ETV)
  • Ventriculoperitoneal shunt (VPS)
📍

Where

1 site
Department of Neurosurgery, University Hospital of Basel
Basel, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy