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Comparing Two Doses of Oral Melatonin as Premedication in Children Undergoing Surgery

RecruitingNAAges 4 Years - 10 YearsAllAl-Azhar University
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In plain words

What the trial is, and whether it could suit you

Preoperative anxiety is a common issue in pediatric anesthesia. Children often experience anxiety and uneasiness due to uncertain outcomes. Surgery and anesthesia are among the most traumatic experiences for children, often considered anxiety-inducing medical treatments. Because they lack control over their environment and circumstances, children undergoing medical procedures typically experience significant unease or anxiety. Several studies have reported that 50%-80% of children experience preoperative anxiety. In order to reduce kids anxiety intensity, several measures are utilized. These strategies are either pharmacological, psychological, or behavioural. Benzodiazepines are popular drugs that can reduce anxiety in children. The most used one in premedication is midazolam. It is a rapid-acting benzodiazepine that has a short elimination half-life. It has sedative, anxiolytic, hypno

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients of either sex * age from 4 to 14 years * Patients with American society Anesthesiologist physical status I and II * Patients undergoing elective surgeries Exclusion Criteria: * ASA more than III * Drug allergy. * Gastrointestinal disorders.
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What it tests

  • melatonin (Circadin ®) 0.2 mg/kg
  • melatonin (Circadin ®) 0.4 mg/kg
  • placebo group
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Where

2 sites
Facualty of Pharmacy, Al Azhar University
Cairo, Egypt
Al-Ayen Univerisity
Madīnat Bābil, Iraq
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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