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Extended Perioperative Administration of Fibrinolysis Inhibitors After Cardiac Surgery

RecruitingNAAges 18 Years - anyAllSaint Petersburg State University, Russia
NCT06493227 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

PRIORITY is a pragmatic, multi-center, cluster crossover trial that aims to evaluate whether implementing a policy of routine extended (intraoperative and 4 hour after transfer to ICU) use of fibrinolysis inhibitors leads to a decrease in post-operative blood transfusion compared to a policy that only involves intraoperative use.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. A hospital that performs a minimum of 250 open heart interventions per year. 2. Consent from hospital physicians regarding the prophylactic use of fibrinolysis inhibitors (more than 95% of physicians involved in the treatment of adult patients (\>18 years) agree to adhere to the strategy of using fibrinolysis inhibitors as prescribed by the study protocol). Exclusion Criteria: * Hospital does not meet inclusion criteria
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What it tests

  • No routine fibrinolysis inhibitors after surgery
  • Routine fibrinolysis inhibitors after surgery
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Where

2 sites
Cardiac surgery department, Saint-Petersburg state university hospital
Saint Petersburg, Russia
St. Petersburg State University Hospital
Saint Petersburg, Russia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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