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โ† Trials
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Behavioural Study in Chronic Pain : Creativity and Motivation, and Circuits Involved in Functional MRI

RecruitingNAAges 18 Years - anyAllFondation Ophtalmologique Adolphe de Rothschild
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In plain words

What the trial is, and whether it could suit you

Being creative means having the ability to produce ideas, actions or works that are original and different from what we have already done. This process involves mental flexibility, in particular the association of distant ideas or divergent thinking. This creative potential is complex and depends on a number of factors, both internal (personality, motivation, emotional state, stress) and external to the individual (socio-cultural context). The generation of creative ideas involves the fronto-striatal circuit, with a balance between flexibility and perseverance. The striatum is central to the reward system and mental flexibility, while the prefrontal cortex is involved in executive control, underpinning perseverance functions. Dopamine plays a key role in this balance, and changes in dopamine levels, depending on the type of receptor activated, will have a direct impact on the transition

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Patient aged 18 and over * Consent to participate in the study * Available for protocol visits * Treated for chronic pain Exclusion Criteria: * Progressive neurodegenerative neurological pathology impairing cognitive function * Untreated clinical depressive syndrome * Fibromyalgia in the foreground * High doses of opioid treatment (greater than 100 mg/d of morphine equivalent) * Impaired judgement or inability to receive information that prevents performance of behavioural tasks * Absolute contraindication to MRI (e.g. pacemaker and implantable stimulator not MRI compatible, intra-orbital metallic foreign body); * Persons benefiting from a legal protection measure * Pregnant or breast-feeding women * Patient deprived of liberty * Patient suffering from mental disorders
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What it tests

  • art-therapy
  • relaxation
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Where

1 site
Fondation Adolphe de Rothschild
Paris, France
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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