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โ† Trials
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Respiratory Tract Microbiome and Probiotics in Children With Cleft Palate

RecruitingNAAges 6 Months - 2 YearsAllUniversity Hospital, Antwerp
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In plain words

What the trial is, and whether it could suit you

Otitis media with effusion (OME) involves fluid accumulation in the middle ear without infection, sometimes causing discomfort and hearing loss in children. Persistent middle ear fluid lasting over 3 months may require treatment, including placement of ventilation tubes if it affects hearing. Children with a cleft palate are at higher risk for otorrea after ventilation tube placement. Treatment typically involves antibiotic drops and ear cleaning by an ENT doctor, often requiring repeated visits, which may impact quality of life for both the child and the parents. The mouth, throat, and nose harbor bacteria that can influence ear infections. This study aims to determine if probiotics can alter the bacteria in the nasopharynx and middle ear fluid and reduce the number of episodes of eardischarge following ventilation tube placement in children with cleft palate. Using Lacticaseibacillu

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * cleft palate \& lip (uni/bilateral) or cleft palate * No syndromal disorders Exclusion Criteria: * syndromal disorder * history of ventilation tube placement
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What it tests

  • Probactiol Baby
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Where

1 site
University Hospital Antwerp
Edegem, Belgium
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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