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CT-Angiography Plaque Characteristics and Events in Deferral Patients by Invasive Fractional Flow Reserve

Recruitingn/aAges 20 Years - anyAllFujita Health University
NCT06508697 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Fractional flow reserve (FFR)-guided PCI for chronic coronary syndromes (CCS) is reported to improve the outcomes compared with angiography-guided PCI. However, cardiac-events still occur in FFR-deferral patients in long-term follow-up. Coronary computed tomography angiography (CTA)-defined high-risk-plaque (HRP) is known to relate future cardiac events. The investigators hypothesized that CTA might identify plaque features linked to future cardiac events in deferral patients.

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📋 Eligibility rules (as published)
Inclusion Criteria: * men and women aged ≥20 years, * patients having chronic coronary syndromes (CCS, * Coronary computed tomography angiography (CTA) was performed within 90 days before invasive coronary angiography (ICA) with fractional flow reserve (FFR) pressure measurement. Exclusion Criteria: * patients with a history of coronary bypass grafting (CABG) because CABG changed local coronary flow dynamics, * patients with left-main disease, * patients with fractional flow reserve (FFR) in stented vessels due to inability to estimate plaque morphology in the stented lesion by coronary computed tomography angiography.
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What it tests

  • invasive coronary angiography (ICA) with fractional flow reserve (FFR) pressure measurement
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Where

1 site
Fujita Health University
Toyoake, Japan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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