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โ† Trials
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Primary Aldosteronism: Superselective Embolization vs. Laparoscopic Endocrine Curative Therapy

RecruitingNAAges 18 Years - 60 YearsAllXinjiang Medical University
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In plain words

What the trial is, and whether it could suit you

The aim of this study was to compare the efficacy and safety of adrenalectomy and superselective adrenal artery embolization in a prospective, multicenter, randomized controlled study. To provide a new interventional alternative therapy for primary aldosteronism.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age 18-60 * Diagnosed with primary aldosteronism according to the 2016 Clinical guidelines of the International Endocrine Society * Primary aldosteronism diagnosed according to international guidelines Unilateral disease by AVS or PET-CT criteria * Patients and their family members signed informed consent and agreed to participate in the study Exclusion Criteria: * A history of severe hypersensitivity to contrast media * Severe liver disease complications, such as thrombocytopenia, esophageal varices rupture bleeding, etc * Renal insufficiency (serum creatinine \> 176mmol/L or estimated glomerular filtration rate \< min.1.73m2) * Combined with other secondary hypertension, such as pheochromocytoma, hypercortisolism, renal vascular hypertension (such as renal artery stenosis), renin secretory tumor, renal parenchymatous hypertension, drug-induced hypertension (such as long-term use of glucocorticoids, contraceptives, estrogen, herbal medicines containing glycyrrhizin), pregnancy hypertension and other secondary hypertension * Combined with genetic diseases: such as false aldosteronism (Liddle syndrome), Bartter syndrome, familial hypokalemia and hypomagnesia (Gitelman syndrome) * Stroke, myocardial infarction and stent implantation occurred in the past 3 months * Serious other diseases, such as heart dysfunction (grade IV), acute infections, autoimmune diseases, various malignant tumors, etc * Participated in other clinical trials within the past 3 months * Pregnant, breastfeeding, or planning a pregnancy * Identify patients with alcohol allergy
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What it tests

  • Superselective adrenal artery embolization or adrenalectomy
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Where

1 site
The First Affiliated Hospital of Xinjiang Medical University
รœrรผmqi, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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