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Early Neurovascular Adaptations in Aging Women

RecruitingEARLY Phase 1Ages 18 Years - 70 YearsFemaleUniversity of Missouri-Columbia
NCT06520982 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Our goal is to enhance our understanding of early vascular adaptations in aging women with an emphasis on the sympathetic nervous system.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Assigned female at birth (AFAB) * 18-70 years of age Exclusion Criteria: * Assigned male at birth (AMAB) * Pregnancy, breastfeeding * Body mass index ≥30 kg/m2 * Taking medications known to affect metabolic, autonomic, and/or respiratory function * Oral hormonal contraception in last 6 month * History of hormone replacement therapy * History of hyster- or oophor-ectomy * Current smoking/Nicotine use * Increased risk of bleeding, pro-coagulant disorders, clotting disorders, anticoagulation therapy * Chronic disease * Blood pressure ≥140/90 mmHg * Communication barriers
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What it tests

  • Norepinephrine
  • Isoproterenol
  • Acetylcholine
  • Nitroprusside
  • Estrogen
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Where

1 site
University of Missouri-Columbia
Columbia, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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