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Periodic Fasting for Treatment of Long Covid in Adults: a Pilot Study

RecruitingNAAges 18 Years - 64 YearsAllUniversity of Luxembourg
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In plain words

What the trial is, and whether it could suit you

Background: Long COVID, characterized by persistent symptoms following acute COVID-19 infection, has emerged as a significant public health concern. Symptoms range from fatigue, cognitive impairments, to respiratory difficulties, affecting patients\' quality of life. Dietary interventions, particularly fasting, have historically been used to modulate immune responses and improve health outcomes in various conditions. The Buchinger-Wilhelmi method represents a structured and medically supervised fasting approach. Given the inflammatory nature of long COVID, fasting may offer therapeutic benefits by modulating the immune response, enhancing cellular repair mechanisms, and resetting metabolic processes. Objectives: This clinical trial aims to assess the feasibility of a 7-day ambulatory fasting intervention using the Buchinger-Wilhelmi method on long COVID patients as primary objecti

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age 18-64 * Diagnosis Long Covid Syndrome (post-acute COVID-19 symptoms persisting โ‰ฅ12 weeks) * Normal body Mass Index (18.5 to 25 kg/m2) * Marginal Iron status ( PF\< 25 ng/ml) * Able to communicate in and comprehend English and/or German and/or French language * Present written / signed declaration of consent * Ability to understand the patient information and willingness to sign the consent form * Consent to specimen collection and specimen use Exclusion Criteria: * Current underweight condition (body mass index less than 18.5 kg/m2) or weight loss exceeding 3 kg within the last month or 5 kg within the last three months. * Existing / current eating disorder within the past five years (e.g., anorexia, bulimia). * Psychiatric condition that limits understanding of the examination protocol (unable to consent) * Severe internal disease (e.g. kidney deficiency with creatinine \> 2mg/dl), chronic inflammatory illness other than LCS * Participation in another intervention study. * Existing vegan diet or fasting during the last six months * Pregnancy or breastfeeding status. * Presence or suspicion of pre-existing ME/CFS or early autonomous dysfunction * Diagnosis of chronic inflammatory bowel diseases, celiac disease or colorectal cancer according to the guidelines of the German Society of Gastroenterology * Use of anti-psychotic drugs * Antibiotic use during the previous 12 months * Start of novel drug therapy * Contraindication for additional blood draws (e.g. hemoglobin \<10)
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What it tests

  • 7-day ambulatory caloric restriction intervention using the Buchinger-Wilhelmi method
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Where

1 site
Rehaklinik CHNP
Ettelbruck, Luxembourg
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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