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Statin Combined with Amlodipine Treats Primary Aldosteronism

RecruitingPhase 4Ages 18 Years - 70 YearsAllThird Military Medical University
NCT06523465 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The drug treatment for primary aldosteronism (PA) is limited and difficult to improve long-term cardiovascular outcomes. This study plans to enroll patients with primary aldosteronism and randomly divide into 3 groups: scheme 1: Statin combined with amlodipine besylate, scheme 2: Statin combined with Spironolactone and Amlodipine besylate. scheme 3: Amlodipine besylate combined with Spironolactone , to observe the changes in plasma aldosterone level, 24-hour urinary aldosterone, blood pressure, and long-term cardiovascular risk.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Clinical diagnosis of primary aldosteronism Exclusion Criteria: * Allergy to drugs in this study * Pregnancy * Severe liver and kidney dysfunction * Mental illness
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What it tests

  • Simvastatin combined with Amlodipine besylate
  • Simvastatin combined with Spironolactone and Amlodipine besylate.
  • Amlodipine besylate combined Spironolactone
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Where

1 site
No. 10 Changjiang River Branch, Yuzhong District，Chongqing, China
Chongqing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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