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Effect GnRH Agonist Administration in Endometriosis Cyst Patients

RecruitingPhase 3Ages 18 Years - 40 YearsFemaleRumah Sakit Pusat Angkatan Darat Gatot Soebroto
NCT06525155 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Endometriosis is a chronic disease that affects 10-15% of women of childbearing age. The most common symptom is pelvic pain. One of the treatment options that has been proven effective in treating endometriosis symptoms, including endometriosis pain, is triptorelin. Triptorelin has also received a distribution permit in Indonesia for the treatment of endometriosis. However, patient compliance in using this drug is very low due to high medical costs and side effects of the drug. Standard treatment with triptorelin is generally given every 4 weeks. A previous preliminary study showed that triptorelin could be given at 6-week interval and provided treatment results that were no different from those at 4-week interval. This is certainly better, because with longer interval doses it can reduce medical costs, reduce side effects due to hormone suppression and can increase patient compliance i

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📋 Eligibility rules (as published)
Inclusion Criteria: * Female subjects aged 18 to 40 years. * The subjects was diagnosed with endometriosis cysts. * Willing to participate in research and sign informed consent before all research-related activities begin. * Regular menstruation (within 25 - 35 day intervals) in the last 3 months before the study was conducted. Exclusion Criteria: * The patient used hormonal contraception in the last 3 months prior to the study. * Using a GnRH agonist within the past 3 months. * Using the hormone progesterone within the last 3 months * Pregnancy, breastfeeding females * History of osteoporosis * History of blood clotting disorders * History of heart and blood vessel disorders
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What it tests

  • Triptorelin Embonate
  • Triptorelin Embonate
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Where

1 site
Department of Obstetrics and Gynecology Central Army Hospital Gatot Soebroto
Jakarta, Indonesia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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